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Indirubin derivatives induce apoptosis of chronic myelogenous leukemia cells involving inhibition of Stat5 signaling

Indirubin is the major active anti‐tumor component of a traditional Chinese herbal medicine used for treatment of chronic myelogenous leukemia (CML). While previous studies indicate that indirubin is a promising therapeutic agent for CML, the molecular mechanism of action of indirubin is not fully u...

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Detalhes bibliográficos
Main Authors: Nam, Sangkil, Scuto, Anna, Yang, Fan, Chen, WenYong, Park, Sungman, Yoo, Hwa-Seung, Konig, Heiko, Bhatia, Ravi, Cheng, Xinlai, Merz, Karl-Heinz, Eisenbrand, Gerhard, Jove, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361532/
https://ncbi.nlm.nih.gov/pubmed/22387217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2012.02.002
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