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Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells
Stat3 protein has an important role in oncogenesis and is a promising anticancer target. Indirubin, the active component of a traditional Chinese herbal medicine, has been shown previously to inhibit cyclin-dependent kinases, resulting in cell cycle arrest. Here, we show that the indirubin derivativ...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1087919/ https://ncbi.nlm.nih.gov/pubmed/15837920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409467102 |
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