The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia

Growing evidence links abnormal epigenetic control to the development of hematological malignancies. Accordingly, inhibition of epigenetic regulators is emerging as a promising therapeutic strategy. The acetylation status of lysine residues in histone tails is one of a number of epigenetic post-tran...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Giotopoulos, G, Chan, W-I, Horton, SJ, Ruau, D, Gallipoli, P, Fowler, A, Crawley, C, Papaemmanuil, E, Campbell, PJ, Göttgens, B, Van Deursen, JM, Cole, PA, Huntly, BJP
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729186/
https://ncbi.nlm.nih.gov/pubmed/25893291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.92
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