The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia

Growing evidence links abnormal epigenetic control to the development of hematological malignancies. Accordingly, inhibition of epigenetic regulators is emerging as a promising therapeutic strategy. The acetylation status of lysine residues in histone tails is one of a number of epigenetic post-tran...

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Bibliografiset tiedot
Julkaisussa:Oncogene
Päätekijät: Giotopoulos, G, Chan, W-I, Horton, SJ, Ruau, D, Gallipoli, P, Fowler, A, Crawley, C, Papaemmanuil, E, Campbell, PJ, Göttgens, B, Van Deursen, JM, Cole, PA, Huntly, BJP
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729186/
https://ncbi.nlm.nih.gov/pubmed/25893291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.92
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