The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia

Growing evidence links abnormal epigenetic control to the development of hematological malignancies. Accordingly, inhibition of epigenetic regulators is emerging as a promising therapeutic strategy. The acetylation status of lysine residues in histone tails is one of a number of epigenetic post-tran...

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Vydáno v:Oncogene
Hlavní autoři: Giotopoulos, G, Chan, W-I, Horton, SJ, Ruau, D, Gallipoli, P, Fowler, A, Crawley, C, Papaemmanuil, E, Campbell, PJ, Göttgens, B, Van Deursen, JM, Cole, PA, Huntly, BJP
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729186/
https://ncbi.nlm.nih.gov/pubmed/25893291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.92
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