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Somatic drivers of B-ALL in a model of ETV6-RUNX1; Pax5(+/−) leukemia
BACKGROUND: B-cell precursor acute lymphoblastic leukemia (B-ALL) is amongst the leading causes of childhood cancer-related mortality. Its most common chromosomal aberration is the ETV6-RUNX1 fusion gene, with ~25 % of ETV6-RUNX1 patients also carrying PAX5 alterations. METHODS: We have recreated th...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | BMC Cancer |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4542115/ https://ncbi.nlm.nih.gov/pubmed/26269126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1586-1 |
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