Loss of Rassf1a synergises with deregulated Runx2 signaling in tumorigenesis

The tumor suppressor gene RASSF1A is inactivated through point mutation or promoter hypermethylation in many human cancers. In this study, we performed a Sleeping Beauty transposon-mediated insertional mutagenesis screen in Rassf1a null mice to identify candidate genes that collaborate with loss of...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: van der Weyden, Louise, Papaspyropoulos, Angelos, Poulogiannis, George, Rust, Alistair G., Rashid, Mamunur, Adams, David J., Arends, Mark J., O’Neill, Eric
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067151/
https://ncbi.nlm.nih.gov/pubmed/22710434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3343
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars