Druggability Assessment of Allosteric Proteins by Dynamics Simulations in the Presence of Probe Molecules

Por Bakan, Ahmet, Nevins, Neysa, Lakdawala, Ami S., Bahar, Ivet
Publicado em 2012

Calculated conformer energies for organic molecules with multiple polar functionalities are method dependent: Taxol (case study)

Por Lakdawala, Ami, Wang, Minmin, Nevins, Neysa, Liotta, Dennis C, Rusinska-Roszak, Danuta, Lozynski, Marek, Snyder, James P
Publicado em 2001

Characterization of an exosite binding inhibitor of matrix metalloproteinase 13

Por Gooljarsingh, Lata T., Lakdawala, Ami, Coppo, Frank, Luo, Lusong, Fields, Gregg B., Tummino, Peter J., Gontarek, Richard R.
Publicado em 2008

The bioactive Taxol conformation on β-tubulin: Experimental evidence from highly active constrained analogs

Por Ganesh, Thota, Guza, Rebecca C., Bane, Susan, Ravindra, Rudravajhala, Shanker, Natasha, Lakdawala, Ami S., Snyder, James P., Kingston, David G. I.
Publicado em 2004

Evaluation of the Tubulin-Bound Paclitaxel Conformation: Synthesis, Biology and SAR Studies of C-4 to C-3′ Bridged Paclitaxel Analogs

Por Ganesh, Thota, Yang, Chao, Norris, Andrew, Glass, Tom, Bane, Susan, Ravindra, Rudravajhala, Banerjee, Abhijit, Metaferia, Belhu, Thomas, Shala L., Giannakakou, Paraskevi, Alcaraz, Ana A., Lakdawala, Ami S., Snyder, James P., Kingston, David G. I.
Publicado em 2007

A target site for template-based design of measles virus entry inhibitors

Por Plemper, Richard K., Erlandson, Karl J., Lakdawala, Ami S., Sun, Aiming, Prussia, Andrew, Boonsombat, Jutatip, Aki-Sener, Esin, Yalcin, Ismail, Yildiz, Ilkay, Temiz-Arpaci, Ozlem, Tekiner, Betul, Liotta, Dennis C., Snyder, James P., Compans, Richard W.
Publicado em 2004

RIP3 induces apoptosis independent of pro-necrotic kinase activity

Por Mandal, Pratyusha, Berger, Scott B., Pillay, Sirika, Moriwaki, Kenta, Huang, Chunzi, Guo, Hongyan, Lich, John D., Finger, Joshua, Kasparcova, Viera, Votta, Bart, Ouellette, Michael, King, Bryan W., Wisnoski, David, Lakdawala, Ami S., DeMartino, Michael P., Casillas, Linda N., Haile, Pamela A., Sehon, Clark A., Marquis, Robert W., Upton, Jason, Daley-Bauer, Lisa P., Roback, Linda, Ramia, Nancy, Dovey, Cole M., Carette, Jan E., Chan, Francis, Bertin, John, Gough, Peter J., Mocarski, Edward S., Kaiser, William J.
Publicado no Mol Cell (2014)