The use of human CD68 transcriptional regulatory sequences to direct high-level expression of class A scavenger receptor in macrophages in vitro and in vivo

Por Gough, Peter J, Gordon, Siamon, Greaves, David R
Publicado em 2001

Macrophage Class A Scavenger Receptor-Mediated Phagocytosis of Escherichia coli: Role of Cell Heterogeneity, Microbial Strain, and Culture Conditions In Vitro

Por Peiser, Leanne, Gough, Peter J., Kodama, Tatsuhiko, Gordon, Siamon
Publicado em 2000

Macrophage expression of active MMP-9 induces acute plaque disruption in apoE-deficient mice

Por Gough, Peter J., Gomez, Ivan G., Wille, Paul T., Raines, Elaine W.
Publicado em 2006

A RIPK3-Caspase 8 complex mediates atypical pro-IL-1β processing

Por Moriwaki, Kenta, Bertin, John, Gough, Peter J., Chan, Francis Ka-Ming
Publicado no J Immunol (2015)

Kinase-independent function of RIP1, critical for mature T-cell survival and proliferation

Por Dowling, John P, Cai, Yubo, Bertin, John, Gough, Peter J, Zhang, Jianke
Publicado no Cell Death Dis (2016)

Distinct Kinase-Independent Role of RIPK3 in CD11c(+) Mononuclear Phagocytes in Cytokine-Induced Tissue Repair

Por Moriwaki, Kenta, Balaji, Sakthi, Bertin, John, Gough, Peter J., Chan, Francis Ka-Ming
Publicado no Cell Rep (2017)

Oxidation of chylomicron remnant-like particles inhibits their uptake by THP-1 macrophages by apolipoprotein E-dependent processes

Por Bejta, Fatos, Moore, Elizabeth H., Avella, Michael, Gough, Peter J., Suckling, Keith E., Botham, Kathleen M.
Publicado em 2007

Herpes Simplex Virus Suppresses Necroptosis in Human Cells

Por Guo, Hongyan, Omoto, Shinya, Harris, Philip A., Finger, Joshua N., Bertin, John, Gough, Peter J., Kaiser, William J., Mocarski, Edward S.
Publicado no Cell Host Microbe (2015)

Cell-extrinsic TNF collaborates with TRIF signaling to promote Yersinia-induced apoptosis

Por Peterson, Lance W., Philip, Naomi H., Dillon, Christopher P., Bertin, John, Gough, Peter J., Green, Douglas R., Brodsky, Igor E.
Publicado no J Immunol (2016)

Autolytic proteolysis within the function to find domain (FIIND) is required for NLRP1 inflammasome activity.

Por Finger, Joshua N., Lich, John D., Dare, Lauren C., Cook, Michael N., Brown, Kristin K., Duraiswami, Chaya, Bertin, John, Gough, Peter J.
Publicado em 2012

Autolytic Proteolysis within the Function to Find Domain (FIIND) Is Required for NLRP1 Inflammasome Activity

Por Finger, Joshua N., Lich, John D., Dare, Lauren C., Cook, Michael N., Brown, Kristin K., Duraiswami, Chaya, Bertin, John J., Gough, Peter J.
Publicado em 2012

Toll-like Receptor 3-mediated Necrosis via TRIF, RIP3, and MLKL

Por Kaiser, William J., Sridharan, Haripriya, Huang, Chunzi, Mandal, Pratyusha, Upton, Jason W., Gough, Peter J., Sehon, Clark A., Marquis, Robert W., Bertin, John, Mocarski, Edward S.
Publicado em 2013

MMP-9 Sheds the β(2) Integrin Subunit (CD18) from Macrophages

Por Vaisar, Tomáš, Kassim, Sean Y., Gomez, Ivan G., Green, Pattie S., Hargarten, Sara, Gough, Peter J., Parks, William C., Wilson, Carole L., Raines, Elaine W., Heinecke, Jay W.
Publicado em 2009

The mitochondrial phosphatase PGAM5 is dispensable for necroptosis but promotes inflammasome activation in macrophages

Por Moriwaki, Kenta, Luz, Nivea Farias, Balaji, Sakthi, De Rosa, Maria Jose, O’Donnell, Carey L., Gough, Peter J., Bertin, John, Welsh, Raymond M., Chan, Francis Ka-Ming
Publicado no J Immunol (2015)

Endothelial deletion of ADAM17 in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults

Por Wilson, Carole L., Gough, Peter J., Chang, Cindy A., Chan, Christina K., Frey, Jeremy M., Liu, Yonggang, Braun, Kathleen R., Chin, Michael T., Wight, Thomas N., Raines, Elaine W.
Publicado em 2013

A Key Role for the Endothelium in NOD1 Mediated Vascular Inflammation: Comparison to TLR4 Responses

Por Gatheral, Timothy, Reed, Daniel M., Moreno, Laura, Gough, Peter J., Votta, Bart J., Sehon, Clark A., Rickard, David J., Bertin, John, Lim, Eric, Nicholson, Andrew G., Mitchell, Jane A.
Publicado em 2012

RIPK1 and PGAM5 Control Leishmania Replication through Distinct Mechanisms

Por Luz, Nivea Farias, Balaji, Sakthi, Okuda, Kendi, Barreto, Aline Silva, Bertin, John, Gough, Peter J., Gazzinelli, Ricardo, Almeida, Roque P., Bozza, Marcelo T., Borges, Valeria M., Chan, Francis Ka-Ming
Publicado no J Immunol (2016)

RIPK1 protects from TNF-α-mediated liver damage during hepatitis

Por Filliol, Aveline, Piquet-Pellorce, Claire, Le Seyec, Jacques, Farooq, Muhammad, Genet, Valentine, Lucas-Clerc, Catherine, Bertin, John, Gough, Peter J, Dimanche-Boitrel, Marie-Thérèse, Vandenabeele, Peter, Bertrand, Mathieu JM, Samson, Michel
Publicado no Cell Death Dis (2016)

Structure guided design of potent and selective ponatinib-based hybrid inhibitors for RIPK1

Por Najjar, Malek, Suebsuwong, Chalada, Ray, Soumya S., Thapa, Roshan J., Maki, Jenny L., Nogusa, Shoko, Shah, Saumil, Saleh, Danish, Gough, Peter J., Bertin, John, Yuan, Junying, Balachandran, Siddharth, Cuny, Gregory D., Degterev, Alexei
Publicado no Cell Rep (2015)

RIPK1/RIPK3 promotes vascular permeability to allow tumor cell extravasation independent of its necroptotic function

Por Hänggi, Kay, Vasilikos, Lazaros, Valls, Aida Freire, Yerbes, Rosario, Knop, Janin, Spilgies, Lisanne M, Rieck, Kristy, Misra, Tvisha, Bertin, John, Gough, Peter J, Schmidt, Thomas, de Almodòvar, Carmen Ruiz, Wong, W Wei-Lynn
Publicado no Cell Death Dis (2017)