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Herpes Simplex Virus Suppresses Necroptosis in Human Cells
Herpes simplex virus (HSV)1 and HSV2 are significant human pathogens causing recurrent disease. During infection, HSV modulates cell death pathways using the large subunit (R1) of ribonucleotide reductase (RR) to suppress apoptosis by binding to and blocking Caspase 8. Here, we demonstrate that HSV1...
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| Publié dans: | Cell Host Microbe |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4382104/ https://ncbi.nlm.nih.gov/pubmed/25674983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.01.003 |
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