Herpes Simplex Virus Suppresses Necroptosis in Human Cells

Herpes simplex virus (HSV)1 and HSV2 are significant human pathogens causing recurrent disease. During infection, HSV modulates cell death pathways using the large subunit (R1) of ribonucleotide reductase (RR) to suppress apoptosis by binding to and blocking Caspase 8. Here, we demonstrate that HSV1...

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Bibliografski detalji
Izdano u:Cell Host Microbe
Glavni autori: Guo, Hongyan, Omoto, Shinya, Harris, Philip A., Finger, Joshua N., Bertin, John, Gough, Peter J., Kaiser, William J., Mocarski, Edward S.
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382104/
https://ncbi.nlm.nih.gov/pubmed/25674983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.01.003
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