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Manipulation of Apoptosis and Necroptosis Signaling by Herpesviruses
Like apoptosis, necroptosis is an innate immune mechanism that eliminates pathogen-infected cells. Receptor interacting protein kinase (RIP)3 (also called RIPK3) mediates necrotic death by phosphorylating an executioner protein, MLKL, leading to plasma membrane leakage. The pathway is triggered agai...
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| Publicado no: | Med Microbiol Immunol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4520828/ https://ncbi.nlm.nih.gov/pubmed/25828583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00430-015-0410-5 |
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