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Distinct Kinase-Independent Role of RIPK3 in CD11c(+) Mononuclear Phagocytes in Cytokine-Induced Tissue Repair

Receptor interacting protein kinase 3 (RIPK3) induces necroptosis, a type of regulated necrosis, through its kinase domain and RIP homotypic interaction motif (RHIM). In addition, RIPK3 has been shown to regulate NLRP3 inflammasome and NF-κB activation. However, the relative contribution of these si...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Moriwaki, Kenta, Balaji, Sakthi, Bertin, John, Gough, Peter J., Chan, Francis Ka-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343671/
https://ncbi.nlm.nih.gov/pubmed/28273458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.02.015
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