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A RIPK3-Caspase 8 complex mediates atypical pro-IL-1β processing
Caspase 8, the initiator caspase for death receptor induced apoptosis, functions as a negative regulator of receptor interacting protein kinase 3 (RIPK3), an essential factor for TNF-, TLR3- or TLR4-induced necroptosis. In certain situations, caspase 8 can also participate in pro-IL-1β processing. H...
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| Publicat a: | J Immunol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4324020/ https://ncbi.nlm.nih.gov/pubmed/25567679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402167 |
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