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The death-inducing activity of RIPK1 is regulated by the pH environment

Receptor interacting protein kinase 1 (RIPK1) is a serine/threonine kinase that dictates whether cells survive or die in response to the cytokine tumor necrosis factor (TNF) and other inflammatory stimuli. The activity of RIPK1 is tightly controlled by multiple posttranslational modification mechani...

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Bibliographic Details
Published in:Sci Signal
Main Authors: Moriwaki, Kenta, Balaji, Sakthi, Chan, Francis Ka-Ming
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337977/
https://ncbi.nlm.nih.gov/pubmed/32398349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aay7066
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