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Regulation of RIPK3- and RHIM-dependent Necroptosis by the Proteasome

Receptor-interacting protein kinase 3 (RIPK3) is a serine/threonine kinase with essential function in necroptosis. The activity of RIPK3 is controlled by phosphorylation. Once activated, RIPK3 phosphorylates and activates the downstream effector mixed lineage kinase domain-like (MLKL) to induce necr...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Moriwaki, Kenta, Chan, Francis Ka-Ming
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786728/
https://ncbi.nlm.nih.gov/pubmed/26786097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.700997
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