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Regulation of RIPK3- and RHIM-dependent Necroptosis by the Proteasome
Receptor-interacting protein kinase 3 (RIPK3) is a serine/threonine kinase with essential function in necroptosis. The activity of RIPK3 is controlled by phosphorylation. Once activated, RIPK3 phosphorylates and activates the downstream effector mixed lineage kinase domain-like (MLKL) to induce necr...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4786728/ https://ncbi.nlm.nih.gov/pubmed/26786097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.700997 |
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