A Key Role for the Endothelium in NOD1 Mediated Vascular Inflammation: Comparison to TLR4 Responses

Understanding the mechanisms by which pathogens induce vascular inflammation and dysfunction may reveal novel therapeutic targets in sepsis and related conditions. The intracellular receptor NOD1 recognises peptidoglycan which features in the cell wall of Gram negative and some Gram positive bacteri...

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Detalhes bibliográficos
Main Authors: Gatheral, Timothy, Reed, Daniel M., Moreno, Laura, Gough, Peter J., Votta, Bart J., Sehon, Clark A., Rickard, David J., Bertin, John, Lim, Eric, Nicholson, Andrew G., Mitchell, Jane A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411636/
https://ncbi.nlm.nih.gov/pubmed/22870324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042386
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