Influence of the RNase H domain of retroviral reverse transcriptases on the metal specificity and substrate selection of their polymerase domains

Por Talele, Tanaji T, Upadhyay, Alok, Pandey, Virendra N
Publicado em 2009

Destabilization of tRNA(3)(Lys) from the primer-binding site of HIV-1 genome by anti-A loop polyamide nucleotide analog

Por Kaushik, Neerja, Talele, Tanaji T., Monel, Raymond, Palumbo, Paul, Pandey, Virendra N.
Publicado em 2001

Pharmacophore Modeling of Nilotinib as an Inhibitor of ATP-Binding Cassette Drug Transporters and BCR-ABL Kinase Using a Three-Dimensional Quantitative Structure–Activity Relations...

Por Shukla, Suneet, Kouanda, Abdul, Silverton, Latoya, Talele, Tanaji T., Ambudkar, Suresh V.
Publicado em 2014

In Vitro Antibacterial Activity of Rhodanine Derivatives against Pathogenic Clinical Isolates

Por AbdelKhalek, Ahmed, Ashby, Charles R., Patel, Bhargav A., Talele, Tanaji T., Seleem, Mohamed N.
Publicado no PLoS One (2016)

Synthesis and SAR optimization of diketo acid pharmacophore for HCV NS5B polymerase inhibition

Por Bhatt, Aaditya, Gurukumar, K. R., Basu, Amartya, Patel, Maulik R., Kaushik-Basu, Neerja, Talele, Tanaji T.
Publicado em 2011

Structure-based virtual screening, synthesis and SAR of novel inhibitors of hepatitis C virus NS5B polymerase

Por Talele, Tanaji T., Arora, Payal, Kulkarni, Shridhar S., Patel, Maulik R., Singh, Satyakam, Chudayeu, Maksim, Kaushik-Basu, Neerja
Publicado em 2010

Multiple Transport-Active Binding Sites Are Available for a Single Substrate on Human P-Glycoprotein (ABCB1)

Por Chufan, Eduardo E., Kapoor, Khyati, Sim, Hong-May, Singh, Satyakam, Talele, Tanaji T., Durell, Stewart R., Ambudkar, Suresh V.
Publicado em 2013

Design, synthesis and biological evaluation of (S)-valine thiazole-derived cyclic and non-cyclic peptidomimetic oligomers as modulators of human P-glycoprotein (ABCB1)

Por Singh, Satyakam, Prasad, Nagarajan Rajendra, Kapoor, Khyati, Chufan, Eduardo E., Patel, Bhargav A., Ambudkar, Suresh V., Talele, Tanaji T.
Publicado em 2013

2-Heteroarylimino-5-arylidene-4-thiazolidinones as a new class of non-nucleoside inhibitors of HCV NS5B polymerase

Por Küçükgüzel, İlkay, Satilmiş, Gökhan, Gurukumar, K.R., Basu, Amartya, Tatar, Esra, Nichols, Daniel B., Talele, Tanaji T., Kaushik-Basu, Neerja
Publicado em 2013

Lamellarin O, a Pyrrole Alkaloid from an Australian Marine Sponge, Ianthella sp., Reverses BCRP Mediated Drug Resistance in Cancer Cells

Por Huang, Xiao-Cong, Xiao, Xue, Zhang, Yun-Kai, Talele, Tanaji T., Salim, Angela A., Chen, Zhe-Sheng, Capon, Robert J.
Publicado em 2014

Bafetinib (INNO-406) reverses multidrug resistance by inhibiting the efflux function of ABCB1 and ABCG2 transporters

Por Zhang, Yun-Kai, Zhang, Guan-Nan, Wang, Yi-Jun, Patel, Bhargav A., Talele, Tanaji T., Yang, Dong-Hua, Chen, Zhe-Sheng
Publicado no Sci Rep (2016)

Glutamine side chain at position 91 on the β5a-β5b loop of Human Immunodeficiency Virus Type 1 Reverse Transcriptase is required for stabilizing the dNTP binding pocket

Por Pandey, Nootan, Mishra, Chaturbhuj A., Manvar, Dinesh, Upadhyay, Alok K., Talele, Tanaji T., Comollo, Thomas W., Kaushik-Basu, Neerja, Pandey, Virendra N.
Publicado em 2011

Telatinib reverses chemotherapeutic multidrug resistance mediated by ABCG2 efflux transporter in vitro and in vivo

Por Sodani, Kamlesh, Patel, Atish, Anreddy, Nagaraju, Singh, Satyakam, Yang, Dong-Hua, Kathawala, Rishil J, Kumar, Priyank, Talele, Tanaji T, Chen, Zhe-Sheng
Publicado em 2014

Design and Synthesis of Human ABCB1 (P-Glycoprotein) Inhibitors by Peptide Coupling of Diverse Chemical Scaffolds on Carboxyl and Amino Termini of (S)-Valine-Derived Thiazole Amino...

Por Singh, Satyakam, Prasad, Nagarajan Rajendra, Chufan, Eduardo E., Patel, Bhargav A., Wang, Yi-Jun, Chen, Zhe-Sheng, Ambudkar, Suresh V., Talele, Tanaji T.
Publicado em 2014

GW583340 and GW2974, human EGFR and HER-2 inhibitors, reverse ABCG2- and ABCB1-mediated drug resistance

Por Sodani, Kamlesh, Tiwari, Amit K., Singh, Satyakam, Patel, Atish, Xiao, Zhi-Jie, Chen, Jun-Jiang, Sun, Yue-Li, Talele, Tanaji T., Chen, Zhe-Sheng
Publicado em 2012

Identification and characterization of coumestans as novel HCV NS5B polymerase inhibitors

Por Kaushik-Basu, Neerja, Bopda-Waffo, Alain, Talele, Tanaji T., Basu, Amartya, Costa, Paulo R. R., da Silva, Alcides J. M., Sarafianos, Stefan G., Noël, François
Publicado em 2008

Masitinib antagonizes ATP-binding cassette subfamily G member 2-mediated multidrug resistance

Por KATHAWALA, RISHIL J., CHEN, JUN-JIANG, ZHANG, YUN-KAI, WANG, YI-JUN, PATEL, ATISH, WANG, DE-SHEN, TALELE, TANAJI T., ASHBY, CHARLES R., CHEN, ZHE-SHENG
Publicado em 2014

Discovery and Structure–Activity Relationship of Novel 2,3-Dihydrobenzofuran-7-carboxamide and 2,3-Dihydrobenzofuran-3(2H)-one-7-carboxamide Derivatives as Poly(ADP-ribose)polymera...

Por Patel, Maulik R., Bhatt, Aaditya, Steffen, Jamin D., Chergui, Adel, Murai, Junko, Pommier, Yves, Pascal, John M., Trombetta, Louis D., Fronczek, Frank R., Talele, Tanaji T.
Publicado em 2014

Elucidation of the structural basis of interaction of the BCR-ABL kinase inhibitor, nilotinib (Tasigna(®)) with the human ABC drug transporter P-glycoprotein

Por Shukla, Suneet, Chufan, Eduardo E., Singh, Satyakam, Skoumbourdis, Amanda P., Kapoor, Khyati, Boxer, Matthew B., Duveau, Damien Y., Thomas, Craig J., Talele, Tanaji T., Ambudkar, Suresh V.
Publicado em 2014

Motesanib (AMG706), a potent multikinase inhibitor, antagonizes multidrug resistance by inhibiting the efflux activity of the ABCB1

Por Wang, Yi-Jun, Kathawala, Rishil J., Zhang, Yun-Kai, Patel, Atish, Kumar, Priyank, Shukla, Suneet, Fung, King Leung, Ambudkar, Suresh V., Talele, Tanaji T., Chen, Zhe-Sheng
Publicado em 2014