A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function

door Fung, King Leung, Gottesman, Michael M.
Gepubliceerd in 2009

Mechanical properties of the tumor stromal microenvironment probed in vitro and ex vivo by in situ-calibrated optical trap-based active microrheology

door Staunton, Jack R, Vieira, Wilfred, Fung, King Leung, Lake, Ross, Devine, Alexus, Tanner, Kandice
Gepubliceerd in Cell Mol Bioeng (2016)

A Dual-Fluorescence High-Throughput Cell Line System for Probing Multidrug Resistance

door Brimacombe, Kyle R., Hall, Matthew D., Auld, Douglas S., Inglese, James, Austin, Christopher P., Gottesman, Michael M., Fung, King-Leung
Gepubliceerd in 2009

Using the BacMam Baculovirus System to Study Expression and Function of Recombinant Efflux Drug Transporters in Polarized Epithelial Cell Monolayers

door Fung, King Leung, Kapoor, Khyati, Pixley, Jessica N., Talbert, Darrell J., Kwit, Alexandra D.T., Ambudkar, Suresh V., Gottesman, Michael M.
Gepubliceerd in Drug Metab Dispos (2016)

Uptake of Compounds That Selectively Kill Multidrug-Resistant Cells: The Copper Transporter SLC31A1 (CTR1) Increases Cellular Accumulation of the Thiosemicarbazone NSC73306

door Fung, King Leung, Tepede, Abisola K., Pluchino, Kristen M., Pouliot, Lynn M., Pixley, Jessica N., Hall, Matthew D., Gottesman, Michael M.
Gepubliceerd in 2014

Expression of the multidrug transporter P-glycoprotein is inversely related to that of apoptosis-associated endogenous TRAIL

door Souza, Paloma S., Madigan, James P., Gillet, Jean-Pierre, Kapoor, Khyati, Ambudkar, Suresh V., Maia, Raquel C., Gottesman, Michael M., Fung, King Leung
Gepubliceerd in Exp Cell Res (2015)

MDR1 Synonymous Polymorphisms Alter Transporter Specificity and Protein Stability in a Stable Epithelial Monolayer

door Fung, King Leung, Pan, James, Ohnuma, Shinobu, Lund, Paul E., Pixley, Jessica N., Kimchi-Sarfaty, Chava, Ambudkar, Suresh V., Gottesman, Michael M.
Gepubliceerd in Cancer Res (2013)

Tariquidar Is an Inhibitor and Not a Substrate of Human and Mouse P-glycoprotein

door Weidner, Lora D., Fung, King Leung, Kannan, Pavitra, Moen, Janna K., Kumar, Jeyan S., Mulder, Jan, Innis, Robert B., Gottesman, Michael M., Hall, Matthew D.
Gepubliceerd in Drug Metab Dispos (2016)

Mitogen-activated protein kinase signaling causes malignant melanoma cells to differentially alter extracellular matrix biosynthesis to promote cell survival

door Afasizheva, Anna, Devine, Alexus, Tillman, Heather, Fung, King Leung, Vieira, Wilfred D., Blehm, Benjamin H., Kotobuki, Yorihisa, Busby, Ben, Chen, Emily I., Tanner, Kandice
Gepubliceerd in BMC Cancer (2016)

Motesanib (AMG706), a potent multikinase inhibitor, antagonizes multidrug resistance by inhibiting the efflux activity of the ABCB1

door Wang, Yi-Jun, Kathawala, Rishil J., Zhang, Yun-Kai, Patel, Atish, Kumar, Priyank, Shukla, Suneet, Fung, King Leung, Ambudkar, Suresh V., Talele, Tanaji T., Chen, Zhe-Sheng
Gepubliceerd in 2014

Synthesis and characterization of a BODIPY conjugate of the BCR-ABL kinase inhibitor Tasigna® (Nilotinib): Evidence for transport of Tasigna® and its fluorescent derivative by ABC...

door Shukla, Suneet, Skoumbourdis, Amanda P., Walsh, Martin J., Hartz, Anika M.S., Fung, King Leung, Wu, Chung-Pu, Gottesman, Michael M., Bauer, Björn, Thomas, Craig J., Ambudkar, Suresh V.
Gepubliceerd in 2011