Expression of the multidrug transporter P-glycoprotein is inversely related to that of apoptosis-associated endogenous TRAIL

Multidrug resistance (MDR) has been associated with expression of ABC transporter genes including P-glycoprotein (Pgp, MDR1, ABCB1). However, deregulation of apoptotic pathways also renders cells resistant to chemotherapy. To discover apoptosis-related genes affected by Pgp expression, we used the H...

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Detalhes bibliográficos
Publicado no:Exp Cell Res
Main Authors: Souza, Paloma S., Madigan, James P., Gillet, Jean-Pierre, Kapoor, Khyati, Ambudkar, Suresh V., Maia, Raquel C., Gottesman, Michael M., Fung, King Leung
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522412/
https://ncbi.nlm.nih.gov/pubmed/26101157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2015.06.005
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