Multidrug resistance associated proteins in multidrug resistance

Por Sodani, Kamlesh, Patel, Atish, Kathawala, Rishil J., Chen, Zhe-Sheng
Publicado em 2012

Recent advances regarding the role of ABC subfamily C member 10 (ABCC10) in the efflux of antitumor drugs

Por Kathawala, Rishil J., Wang, Yi-Jun, Ashby, Charles R., Chen, Zhe-Sheng
Publicado em 2014

Repositioning of Tyrosine Kinase Inhibitors as Antagonists of ATP-Binding Cassette Transporters in Anticancer Drug Resistance

Por Wang, Yi-Jun, Zhang, Yun-Kai, Kathawala, Rishil J., Chen, Zhe-Sheng
Publicado no Cancers (Basel) (2014)

PD173074, a selective FGFR inhibitor, reverses MRP7 (ABCC10)-mediated MDR

Por Anreddy, Nagaraju, Patel, Atish, Sodani, Kamlesh, Kathawala, Rishil J., Chen, Eugenie P., Wurpel, John N.D., Chen, Zhe-Sheng
Publicado no Acta Pharm Sin B (2014)

2-Trifluoromethyl-2-Hydroxypropionamide Derivatives as Novel Reversal Agents of ABCG2 (BCRP)-Mediated Multidrug Resistance: Synthesis and Biological Evaluations

Por Kathawala, Rishil J., Li, Tianwen, Yang, Danwen, Guo, Hui-Qin, Yang, Dong-Hua, Chen, Xiang, Cheng, Changmei, Chen, Zhe-Sheng
Publicado no J Cell Biochem (2017)

Telatinib reverses chemotherapeutic multidrug resistance mediated by ABCG2 efflux transporter in vitro and in vivo

Por Sodani, Kamlesh, Patel, Atish, Anreddy, Nagaraju, Singh, Satyakam, Yang, Dong-Hua, Kathawala, Rishil J, Kumar, Priyank, Talele, Tanaji T, Chen, Zhe-Sheng
Publicado em 2014

Tandutinib (MLN518) reverses multidrug resistance by inhibiting the efflux activity of the multidrug resistance protein 7 (ABCC10)

Por DENG, WEN, DAI, CHUN-LING, CHEN, JUN-JIANG, KATHAWALA, RISHIL J., SUN, YUE-LI, CHEN, HAI-FAN, FU, LI-WU, CHEN, ZHE-SHENG
Publicado em 2013

ATP-binding cassette subfamily B member 1 (ABCB1) and subfamily C member 10 (ABCC10) are not primary resistance factors for cabazitaxel

Por Kathawala, Rishil J, Wang, Yi-Jun, Shukla, Suneet, Zhang, Yun-Kai, Alqahtani, Saeed, Kaddoumi, Amal, Ambudkar, Suresh V, Ashby, Charles R, Chen, Zhe-Sheng
Publicado no Chin J Cancer (2015)

Semi-synthetic ocotillol analogues as selective ABCB1-mediated drug resistance reversal agents

Por Zhang, Yun-Kai, Zhang, Hengyuan, Zhang, Guan-Nan, Wang, Yi-Jun, Kathawala, Rishil J., Si, Rui, Patel, Bhargav A., Xu, Jinyi, Chen, Zhe-Sheng
Publicado no Oncotarget (2015)

Masitinib Antagonizes ATP-Binding Cassette Subfamily C Member 10-Mediated Paclitaxel Resistance: A Preclinical Study

Por Kathawala, Rishil J., Sodani, Kamlesh, Chen, Kang, Patel, Atish, Abuznait, Alaa H., Anreddy, Nagaraju, Sun, Yue-Li, Kaddoumi, Amal, Ashby, Charles R., Chen, Zhe-Sheng
Publicado em 2014

Masitinib antagonizes ATP-binding cassette subfamily G member 2-mediated multidrug resistance

Por KATHAWALA, RISHIL J., CHEN, JUN-JIANG, ZHANG, YUN-KAI, WANG, YI-JUN, PATEL, ATISH, WANG, DE-SHEN, TALELE, TANAJI T., ASHBY, CHARLES R., CHEN, ZHE-SHENG
Publicado em 2014

Motesanib (AMG706), a potent multikinase inhibitor, antagonizes multidrug resistance by inhibiting the efflux activity of the ABCB1

Por Wang, Yi-Jun, Kathawala, Rishil J., Zhang, Yun-Kai, Patel, Atish, Kumar, Priyank, Shukla, Suneet, Fung, King Leung, Ambudkar, Suresh V., Talele, Tanaji T., Chen, Zhe-Sheng
Publicado em 2014

WHI-P154 enhances the chemotherapeutic effect of anticancer agents in ABCG2-overexpressing cells

Por Zhang, Hui, Zhang, Yun-Kai, Wang, Yi-Jun, Kathawala, Rishil J, Patel, Atish, Zhu, Hua, Sodani, Kamlesh, Talele, Tanaji T, Ambudkar, Suresh V, Chen, Zhe-Sheng, Fu, Li-Wu
Publicado no Cancer Sci (2014)

The small molecule tyrosine kinase inhibitor NVP-BHG712 antagonizes ABCC10-mediated paclitaxel resistance: a preclinical and pharmacokinetic study

Por Kathawala, Rishil J., Wei, Liuya, Anreddy, Nagaraju, Chen, Kang, Patel, Atish, Alqahtani, Saeed, Zhang, Yun-Kai, Wang, Yi-Jun, Sodani, Kamlesh, Kaddoumi, Amal, Ashby, Charles R., Chen, Zhe-Sheng
Publicado no Oncotarget (2014)

ARRY-334543 reverses multidrug resistance by antagonizing the activity of ATP-binding cassette subfamily G member 2

Por Wang, De-Shen, Patel, Atish, Sim, Hong-May, Zhang, Yun-Kai, Wang, Yi-Jun, Kathawala, Rishil J., Zhang, Hui, Talele, Tanaji T., Ambudkar, Suresh V., Xu, Rui-Hua, Chen, Zhe-Sheng
Publicado em 2014

In vitro, in vivo and ex vivo characterization of ibrutinib: a potent inhibitor of the efflux function of the transporter MRP1

Por Zhang, Hui, Patel, Atish, Ma, Shao-Lin, Li, Xiao Jie, Zhang, Yun-Kai, Yang, Pei-Qi, Kathawala, Rishil J, Wang, Yi-Jun, Anreddy, Nagaraju, Fu, Li-Wu, Chen, Zhe-Sheng
Publicado no Br J Pharmacol (2014)

A-803467, a tetrodotoxin-resistant sodium channel blocker, modulates ABCG2-mediated MDR in vitro and in vivo

Por Anreddy, Nagaraju, Patel, Atish, Zhang, Yun-Kai, Wang, Yi-Jun, Shukla, Suneet, Kathawala, Rishil J., Kumar, Priyank, Gupta, Pranav, Ambudkar, Suresh V., Wurpel, John N. D., Chen, Zhe-Sheng, Guo, Huiqin
Publicado no Oncotarget (2015)

Icotinib antagonizes ABCG2-mediated multidrug resistance, but not the pemetrexed resistance mediated by thymidylate synthase and ABCG2

Por Wang, De-Shen, Patel, Atish, Shukla, Suneet, Zhang, Yun-Kai, Wang, Yi-Jun, Kathawala, Rishil J., Robey, Robert W., Zhang, Li, Yang, Dong-Hua, Talele, Tanaji T., Bates, Susan E., Ambudkar, Suresh V., Xu, Rui-Hua, Chen, Zhe-Sheng
Publicado em 2014