The Challenge of Exploiting ABCG2 in the Clinic

Por Robey, Robert W., Ierano, Caterina, Zhan, Zhirong, Bates, Susan E.
Publicado em 2011

Sunitinib (Sutent, SU11248), a Small-Molecule Receptor Tyrosine Kinase Inhibitor, Blocks Function of the ATP-Binding Cassette (ABC) Transporters P-Glycoprotein (ABCB1) and ABCG2

Por Shukla, Suneet, Robey, Robert W., Bates, Susan E., Ambudkar, Suresh V.
Publicado em 2009

Multidrug transporters: recent insights from cryo-electron microscopy-derived atomic structures and animal models

Por Lusvarghi, Sabrina, Robey, Robert W., Gottesman, Michael M., Ambudkar, Suresh V.
Publicado no F1000Res (2020)

ABC Transporters: Unvalidated Therapeutic Targets in Cancer and the CNS

Por Robey, Robert W., Massey, Paul R., Amiri-Kordestani, Laleh, Bates, Susan E.
Publicado em 2010

Assessment of Drug Transporter Function Using Fluorescent Cell Imaging

Por Bircsak, Kristin M., Gibson, Christopher J., Robey, Robert W., Aleksunes, Lauren M.
Publicado em 2013

The controversial role of ABC transporters in clinical oncology

Por Tamaki, Akina, Ierano, Caterina, Szakacs, Gergely, Robey, Robert W., Bates, Susan E.
Publicado no Essays Biochem (2011)

Rapid detection of ABC transporter interaction: potential utility in pharmacology

Por Robey, Robert W., Lin, Bo, Qiu, Jean, Chan, Leo Li-Ying, Bates, Susan E.
Publicado em 2010

Mycoplasma Infection Mediates Sensitivity of Multidrug-Resistant Cell Lines to Tiopronin: A Cautionary Tale

Por Huff, Lyn M., Horibata, Sachi, Robey, Robert W., Hall, Matthew D., Gottesman, Michael M.
Publicado no J Med Chem (2020)

Escape from hsa-miR-519c enables drug resistant cells to maintain high expression of ABCG2

Por To, Kenneth K.W., Robey, Robert W., Knutsen, Turid, Zhan, Zhirong, Ried, Thomas, Bates, Susan E.
Publicado em 2009

ABCG2: A Perspective

Por Robey, Robert W., To, Kenneth K. K., Polgar, Orsolya, Dohse, Marius, Fetsch, Patricia, Dean, Michael, Bates, Susan E.
Publicado em 2008

Histone deacetylase inhibitors: emerging mechanisms of resistance

Por Robey, Robert W., Chakraborty, Arup R., Basseville, Agnes, Luchenko, Victoria, Bahr, Julian, Zhan, Zhirong, Bates, Susan E.
Publicado em 2011

Revisiting the role of efflux pumps in multidrug-resistant cancer

Por Robey, Robert W., Pluchino, Kristen M., Hall, Matthew D., Fojo, Antonio T., Bates, Susan E., Gottesman, Michael M.
Publicado no Nat Rev Cancer (2018)

Porphyrin-lipid Assemblies and Nanovesicles Overcome ABC Transporter-Mediated Photodynamic Therapy Resistance in Cancer Cells

Por Baglo, Yan, Liang, Barry J., Robey, Robert W., Ambudkar, Suresh V., Gottesman, Michael M., Huang, Huang-Chiao
Publicado no Cancer Lett (2019)

The 315–316 deletion determines the BXP-21 antibody epitope but has no effect on the function of wild type ABCG2 or the Q141K variant

Por Polgar, Orsolya, Deeken, John F., Ediriwickrema, Lilangi S., Tamaki, Akina, Steinberg, Seth M., Robey, Robert W., Bates, Susan E.
Publicado em 2008

Reduced Expression of DNA Topoisomerase I in SF295 Human Glioblastoma Cells Selected for Resistance to Homocamptothecin and Diflomotecan

Por Liao, Zhiyong, Robey, Robert W., Guirouilh-Barbat, Josée, To, Kenneth K. W., Polgar, Orsolya, Bates, Susan E., Pommier, Yves
Publicado em 2007

Histone Deacetylase Inhibitors Influence Chemotherapy Transport by Modulating Expression and Trafficking of a Common Polymorphic Variant of the ABCG2 Efflux Transporter

Por Basseville, Agnes, Tamaki, Akina, Ierano, Caterina, Trostel, Shana, Ward, Yvona, Robey, Robert W., Hegde, Ramanujan S., Bates, Susan E.
Publicado em 2012

Leptin Signaling Affects Survival and Chemoresistance of Estrogen Receptor Negative Breast Cancer

Por Lipsey, Crystal C., Harbuzariu, Adriana, Robey, Robert W., Huff, Lyn M., Gottesman, Michael M., Gonzalez-Perez, Ruben R.
Publicado no Int J Mol Sci (2020)

Histone deacetylase inhibitors induce CXCR4 mRNA but antagonize CXCR4 migration

Por Ierano, Caterina, Basseville, Agnes, To, Kenneth K.W., Zhan, Zhirong, Robey, Robert W., Wilkerson, Julia, Bates, Susan E., Scala, Stefania
Publicado em 2013

Mutational Analysis of Threonine 402 Adjacent to the GXXXG Dimerization Motif in TM1 of ABCG2

Por Polgar, Orsolya, Ierano, Caterina, Tamaki, Akina, Stanley, Bradford, Ward, Yvona, Xia, Di, Tarasova, Nadya, Robey, Robert W., Bates, Susan E.
Publicado em 2010

Overlapping Substrate and Inhibitor Specificity of Human and Murine ABCG2

Por Bakhsheshian, Joshua, Hall, Matthew D., Robey, Robert W., Herrmann, Michelle A., Chen, Jin-Qiu, Bates, Susan E., Gottesman, Michael M.
Publicado em 2013