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The controversial role of ABC transporters in clinical oncology
The phenomenon of multidrug resistance in cancer is often associated with the overexpression of the ABC (ATP-binding cassette) transporters Pgp (P-glycoprotein) (ABCB1), MRP1 (multidrug resistance-associated protein 1) (ABCC1) and ABCG2 [BCRP (breast cancer resistance protein)]. Since the discovery...
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| Udgivet i: | Essays Biochem |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6944313/ https://ncbi.nlm.nih.gov/pubmed/21967059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/bse0500209 |
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