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Rapid detection of ABC transporter interaction: potential utility in pharmacology

INTRODUCTION: The ATP-binding cassette (ABC) transporters P-glycoprotein (Pgp/ABCB1), multidrug resistance-associated protein 1 (MRP1/ABCC1), and breast cancer resistance protein (BCRP/ABCG2) are known to transport a wide range of structurally diverse compounds. Their high level of expression at the...

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Detalhes bibliográficos
Main Authors: Robey, Robert W., Lin, Bo, Qiu, Jean, Chan, Leo Li-Ying, Bates, Susan E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086650/
https://ncbi.nlm.nih.gov/pubmed/21112407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vascn.2010.11.003
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