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Revisiting the role of efflux pumps in multidrug-resistant cancer
Most patients who die of cancer have disseminated disease that has become resistant to multiple therapeutic modalities. Ample evidence suggests that the expression of ATP- binding cassette (ABC) transporters, especially the multidrug resistance protein 1 (MDR1, also known as P- glycoprotein or P-gp)...
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| Publicado no: | Nat Rev Cancer |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6622180/ https://ncbi.nlm.nih.gov/pubmed/29643473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41568-018-0005-8 |
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