The comings and goings of PARP-1 in response to DNA damage

od Pascal, John M.
Izdano u DNA Repair (Amst) (2018)

The Rise and Fall of Poly (ADP-ribose). An Enzymatic Perspective

od Pascal, John M., Ellenberger, Tom
Izdano u DNA Repair (Amst) (2015)

PARP-1 mechanism for coupling DNA damage detection to poly(ADP-ribose) synthesis

od Langelier, Marie-France, Pascal, John M.
Izdano 2013

New players to the field of ADP-ribosylation make the final cut

od Steffen, Jamin D, Pascal, John M
Izdano 2013

Unstructured to structured transition of an intrinsically disordered protein peptide in coupling Ca(2+)-sensing and SK channel activation

od Zhang, Miao, Pascal, John M., Zhang, Ji-Fang
Izdano 2013

PARP-2 domain requirements for DNA damage-dependent activation and localization to sites of DNA damage

od Riccio, Amanda A., Cingolani, Gino, Pascal, John M.
Izdano u Nucleic Acids Res (2016)

Signal-induced PARP1-Erk synergism mediates IEG expression

od Cohen-Armon, Malka, Yeheskel, Adva, Pascal, John M.
Izdano u Signal Transduct Target Ther (2019)

Structural and functional analysis of parameters governing tankyrase-1 interaction with telomeric repeat-binding factor 1 and GDP-mannose 4,6-dehydratase

od Eisemann, Travis, Langelier, Marie-France, Pascal, John M.
Izdano u J Biol Chem (2019)

PARP-2 and PARP-3 are selectively activated by 5′ phosphorylated DNA breaks through an allosteric regulatory mechanism shared with PARP-1

od Langelier, Marie-France, Riccio, Amanda A., Pascal, John M.
Izdano 2014

The DNA binding domain of human DNA ligase I interacts with both nicked DNA and the DNA sliding clamps, PCNA and hRad9-hRad1-hHus1

od Song, Wei, Pascal, John M., Ellenberger, Tom, Tomkinson, Alan E.
Izdano 2009

Autoregulation of kinase dephosphorylation by ATP binding to AGC protein kinases

od Chan, Tung O, Pascal, John M, Armen, Roger S, Rodeck, Ulrich
Izdano 2012

Structural biology of the writers, readers, and erasers in mono- and poly(ADP-ribose) mediated signaling

od Karlberg, Tobias, Langelier, Marie-France, Pascal, John M., Schüler, Herwig
Izdano 2013

Fluorescent sensors of PARP-1 structural dynamics and allosteric regulation in response to DNA damage

od Steffen, Jamin D., McCauley, Michael M., Pascal, John M.
Izdano u Nucleic Acids Res (2016)

Crystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO DNA-DEPENDENT PARP-1 ACTIVITY

od Langelier, Marie-France, Planck, Jamie L., Roy, Swati, Pascal, John M.
Izdano 2011

Adaptation to tRNA acceptor stem structure by flexible adjustment in the catalytic domain of class I tRNA synthetases

od Liu, Cuiping, Sanders, Jeffrey M., Pascal, John M., Hou, Ya-Ming
Izdano 2012

Structural basis for DNA-dependent poly(ADP-ribosyl)ation by human PARP-1

od Langelier, Marie-France, Planck, Jamie L., Roy, Swati, Pascal, John M.
Izdano 2012

Structural Implications for Selective Targeting of PARPs

od Steffen, Jamin D., Brody, Jonathan R., Armen, Roger S., Pascal, John M.
Izdano 2013

PARP family enzymes: regulation and catalysis of the poly(ADP-ribose) posttranslational modification

od Langelier, Marie-France, Eisemann, Travis, Riccio, Amanda A., Pascal, John M.
Izdano u Curr Opin Struct Biol (2018)

Identification of the functional binding pocket for compounds targeting small-conductance Ca(2+)-activated potassium channels

od Zhang, Miao, Pascal, John M., Schumann, Marcel, Armen, Roger S., Zhang, Ji-fang
Izdano 2012

Tankyrase SAM domain polymerization is required for its role in Wnt signaling

od Riccio, Amanda A., McCauley, Michael, Langelier, Marie-France, Pascal, John M.
Izdano u Structure (2016)