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PARP family enzymes: regulation and catalysis of the poly(ADP-ribose) posttranslational modification

Poly(ADP-ribose) is a posttranslational modification and signaling molecule that regulates many aspects of human cell biology, and it is synthesized by enzymes known as poly(ADP-ribose) polymerases, or PARPs. A diverse collection of domain structures dictates the different cellular roles of PARP enz...

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Publicado en:Curr Opin Struct Biol
Autores principales: Langelier, Marie-France, Eisemann, Travis, Riccio, Amanda A., Pascal, John M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687463/
https://ncbi.nlm.nih.gov/pubmed/30481609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2018.11.002
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