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Unstructured to structured transition of an intrinsically disordered protein peptide in coupling Ca(2+)-sensing and SK channel activation
Most proteins, such as ion channels, form well-organized 3D structures to carry out their specific functions. A typical voltage-gated potassium channel subunit has six transmembrane segments (S1–S6) to form the voltage-sensing domain and the pore domain. Conformational changes of these domains resul...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3607015/ https://ncbi.nlm.nih.gov/pubmed/23487779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220253110 |
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