Coupling of SK channels, L-type Ca(2+) channels, and ryanodine receptors in cardiomyocytes

Small-conductance Ca(2+)-activated K(+) (SK) channels regulate the excitability of cardiomyocytes by integrating intracellular Ca(2+) and membrane potentials on a beat-to-beat basis. The inextricable interplay between activation of SK channels and Ca(2+) dynamics suggests the pathology of one begets...

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Publicat a:Sci Rep
Autors principals: Zhang, Xiao-Dong, Coulibaly, Zana A., Chen, Wei Chun, Ledford, Hannah A., Lee, Jeong Han, Sirish, Padmini, Dai, Gu, Jian, Zhong, Chuang, Frank, Brust-Mascher, Ingrid, Yamoah, Ebenezer N., Chen-Izu, Ye, Izu, Leighton T., Chiamvimonvat, Nipavan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856806/
https://ncbi.nlm.nih.gov/pubmed/29549309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22843-3
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