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Distinct subcellular mechanisms for the enhancement of the surface membrane expression of SK2 channel by its interacting proteins, α‐actinin2 and filamin A

KEY POINTS: Ion channels are transmembrane proteins that are synthesized within the cells but need to be trafficked to the cell membrane for the channels to function. Small‐conductance, Ca(2+)‐activated K(+) channels (SK, K(Ca)2) are unique subclasses of K(+) channels that are regulated by Ca(2+) in...

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Bibliografiske detaljer
Udgivet i:J Physiol
Main Authors: Zhang, Zheng, Ledford, Hannah A., Park, Seojin, Wang, Wenying, Rafizadeh, Sassan, Kim, Hyo Jeong, Xu, Wilson, Lu, Ling, Lau, Victor C., Knowlton, Anne A., Zhang, Xiao‐Dong, Yamoah, Ebenezer N., Chiamvimonvat, Nipavan
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374114/
https://ncbi.nlm.nih.gov/pubmed/27779751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272942
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