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PARP-2 domain requirements for DNA damage-dependent activation and localization to sites of DNA damage
Poly(ADP-ribose) polymerase-2 (PARP-2) is one of three human PARP enzymes that are potently activated during the cellular DNA damage response (DDR). DDR-PARPs detect DNA strand breaks, leading to a dramatic increase in their catalytic production of the posttranslational modification poly(ADP-ribose)...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4770219/ https://ncbi.nlm.nih.gov/pubmed/26704974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1376 |
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