PARP-1 dependent recruitment of the amyotrophic lateral sclerosis-associated protein FUS/TLS to sites of oxidative DNA damage

Amyotrophic lateral sclerosis (ALS) is associated with progressive degeneration of motor neurons. Several of the genes associated with this disease encode proteins involved in RNA processing, including fused-in-sarcoma/translocated-in-sarcoma (FUS/TLS). FUS is a member of the heterogeneous nuclear r...

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Detalhes bibliográficos
Main Authors: Rulten, Stuart L., Rotheray, Amy, Green, Ryan L., Grundy, Gabrielle J., Moore, Duncan A. Q., Gómez-Herreros, Fernando, Hafezparast, Majid, Caldecott, Keith W
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874156/
https://ncbi.nlm.nih.gov/pubmed/24049082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt835
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