Neurobiology of axonal transport defects in motor neuron diseases: Opportunities for translational research?

Por De Vos, Kurt J., Hafezparast, Majid
Publicado no Neurobiol Dis (2017)

Cytoplasmic dynein heavy chain: the servant of many masters

Por Schiavo, Giampietro, Greensmith, Linda, Hafezparast, Majid, Fisher, Elizabeth M.C.
Publicado em 2013

A mutation in dynein rescues axonal transport defects and extends the life span of ALS mice

Por Kieran, Dairin, Hafezparast, Majid, Bohnert, Stephanie, Dick, James R.T., Martin, Joanne, Schiavo, Giampietro, Fisher, Elizabeth M.C., Greensmith, Linda
Publicado em 2005

Mouse Cytoplasmic Dynein Intermediate Chains: Identification of New Isoforms, Alternative Splicing and Tissue Distribution of Transcripts

Por Kuta, Anna, Deng, Wenhan, Morsi El-Kadi, Ali, Banks, Gareth T., Hafezparast, Majid, Pfister, K. Kevin, Fisher, Elizabeth M. C.
Publicado em 2010

Correction: Mouse Cytoplasmic Dynein Intermediate Chains: Identification of New Isoforms, Alternative Splicing and Tissue Distribution of Transcripts

Por Kuta, Anna, Deng, Wenhan, Morsi El-Kadi, Ali, Banks, Gareth T., Hafezparast, Majid, Pfister, K. Kevin, Fisher, Elizabeth M. C.
Publicado em 2010

Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical–induced DNA damage

Por Chiang, Shih-Chieh, Meagher, Martin, Kassouf, Nick, Hafezparast, Majid, McKinnon, Peter J., Haywood, Rachel, El-Khamisy, Sherif F.
Publicado no Sci Adv (2017)

Neurodegenerative Mutation in Cytoplasmic Dynein Alters Its Organization and Dynein-Dynactin and Dynein-Kinesin Interactions

Por Deng, Wenhan, Garrett, Caroline, Dombert, Benjamin, Soura, Violetta, Banks, Gareth, Fisher, Elizabeth M. C., van der Brug, Marcel P., Hafezparast, Majid
Publicado em 2010

PARP-1 dependent recruitment of the amyotrophic lateral sclerosis-associated protein FUS/TLS to sites of oxidative DNA damage

Por Rulten, Stuart L., Rotheray, Amy, Green, Ryan L., Grundy, Gabrielle J., Moore, Duncan A. Q., Gómez-Herreros, Fernando, Hafezparast, Majid, Caldecott, Keith W
Publicado em 2014

Expression of a pathogenic mutation of SOD1 sensitizes aprataxin-deficient cells and mice to oxidative stress and triggers hallmarks of premature ageing

Por Carroll, Jean, Page, Tristan K.W., Chiang, Shih-Chieh, Kalmar, Bernadett, Bode, David, Greensmith, Linda, Mckinnon, Peter J, Thorpe, Julian R., Hafezparast, Majid, El-Khamisy, Sherif F.
Publicado no Hum Mol Genet (2015)

A comprehensive assessment of the SOD1(G93A) low-copy transgenic mouse, which models human amyotrophic lateral sclerosis

Por Acevedo-Arozena, Abraham, Kalmar, Bernadett, Essa, Shafa, Ricketts, Thomas, Joyce, Peter, Kent, Rosie, Rowe, Claire, Parker, Andy, Gray, Anna, Hafezparast, Majid, Thorpe, Julian R., Greensmith, Linda, Fisher, Elizabeth M. C.
Publicado em 2011

The Legs at odd angles (Loa) Mutation in Cytoplasmic Dynein Ameliorates Mitochondrial Function in SOD1(G93A) Mouse Model for Motor Neuron Disease

Por El-Kadi, Ali Morsi, Bros-Facer, Virginie, Deng, Wenhan, Philpott, Amelia, Stoddart, Eleanor, Banks, Gareth, Jackson, Graham S., Fisher, Elizabeth M. C., Duchen, Michael R., Greensmith, Linda, Moore, Anthony L., Hafezparast, Majid
Publicado em 2010

Behavioral and Other Phenotypes in a Cytoplasmic Dynein Light Intermediate Chain 1 Mutant Mouse

Por Banks, Gareth T., Haas, Matilda A., Line, Samantha, Shepherd, Hazel L., AlQatari, Mona, Stewart, Sammy, Rishal, Ida, Philpott, Amelia, Kalmar, Bernadett, Kuta, Anna, Groves, Michael, Parkinson, Nicholas, Acevedo-Arozena, Abraham, Brandner, Sebastian, Bannerman, David, Greensmith, Linda, Hafezparast, Majid, Koltzenburg, Martin, Deacon, Robert, Fainzilber, Mike, Fisher, Elizabeth M. C.
Publicado em 2011

Mutations in BICD2 Cause Dominant Congenital Spinal Muscular Atrophy and Hereditary Spastic Paraplegia

Por Oates, Emily C., Rossor, Alexander M., Hafezparast, Majid, Gonzalez, Michael, Speziani, Fiorella, MacArthur, Daniel G., Lek, Monkol, Cottenie, Ellen, Scoto, Mariacristina, Foley, A. Reghan, Hurles, Matthew, Houlden, Henry, Greensmith, Linda, Auer-Grumbach, Michaela, Pieber, Thomas R., Strom, Tim M., Schule, Rebecca, Herrmann, David N., Sowden, Janet E., Acsadi, Gyula, Menezes, Manoj P., Clarke, Nigel F., Züchner, Stephan, Muntoni, Francesco, North, Kathryn N., Reilly, Mary M.
Publicado em 2013

Novel mutations expand the clinical spectrum of DYNC1H1-associated spinal muscular atrophy

Por Scoto, Mariacristina, Rossor, Alexander M., Harms, Matthew B., Cirak, Sebahattin, Calissano, Mattia, Robb, Stephanie, Manzur, Adnan Y., Martínez Arroyo, Amaia, Rodriguez Sanz, Aida, Mansour, Sahar, Fallon, Penny, Hadjikoumi, Irene, Klein, Andrea, Yang, Michele, De Visser, Marianne, Overweg-Plandsoen, W.C.G. (Truus), Baas, Frank, Taylor, J. Paul, Benatar, Michael, Connolly, Anne M., Al-Lozi, Muhammad T., Nixon, John, de Goede, Christian G.E.L., Foley, A. Reghan, Mcwilliam, Catherine, Pitt, Matthew, Sewry, Caroline, Phadke, Rahul, Hafezparast, Majid, Chong, W.K. “Kling”, Mercuri, Eugenio, Baloh, Robert H., Reilly, Mary M., Muntoni, Francesco
Publicado no Neurology (2015)