Expression of Phosphatidylinositol (4,5) Bisphosphate–specific Pleckstrin Homology Domains Alters Direction But Not the Level of Axonal Transport of Mitochondria

Por De Vos, Kurt J., Sable, Julia, Miller, Kyle E., Sheetz, Michael P.
Publicado em 2003

Protein Homeostasis in Amyotrophic Lateral Sclerosis: Therapeutic Opportunities?

Por Webster, Christopher P., Smith, Emma F., Shaw, Pamela J., De Vos, Kurt J.
Publicado no Front Mol Neurosci (2017)

Phosphorylation of kinesin light chain 1 at serine 460 modulates binding and trafficking of calsyntenin-1

Por Vagnoni, Alessio, Rodriguez, Lilia, Manser, Catherine, De Vos, Kurt J., Miller, Christopher C. J.
Publicado em 2011

Deficiency of the Copper Chaperone for Superoxide Dismutase Increases Amyloid-β Production

Por Gray, Emma H., De Vos, Kurt J., Dingwall, Colin, Perkinton, Michael S., Miller, Christopher C.J.
Publicado em 2010

Axonal Transport Defects in a Mitofusin 2 Loss of Function Model of Charcot-Marie-Tooth Disease in Zebrafish

Por Chapman, Anna L., Bennett, Ellen J., Ramesh, Tennore M., De Vos, Kurt J., Grierson, Andrew J.
Publicado em 2013

Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria

Por Mórotz, Gábor M., De Vos, Kurt J., Vagnoni, Alessio, Ackerley, Steven, Shaw, Christopher E., Miller, Christopher C.J.
Publicado em 2012

A comparison of in vitro properties of resting SOD1 transgenic microglia reveals evidence of reduced neuroprotective function

Por Sargsyan, Siranush A, Blackburn, Daniel J, Barber, Siân C, Grosskreutz, Julian, De Vos, Kurt J, Monk, Peter N, Shaw, Pamela J
Publicado em 2011

Lemur tyrosine kinase-2 signalling regulates kinesin light chain-2 phosphorylation and binding of Smad2 cargo

Por Manser, Catherine, Guillot, Florence, Vagnoni, Alessio, Davies, Jennifer, Lau, Kwok-Fai, McLoughlin, Declan M., De Vos, Kurt J., Miller, Christopher C.J.
Publicado em 2011

Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons

Por Rodríguez-Martín, Teresa, Pooler, Amy M., Lau, Dawn H.W., Mórotz, Gábor M., De Vos, Kurt J., Gilley, Jonathan, Coleman, Michael P., Hanger, Diane P.
Publicado no Neurobiol Dis (2016)

VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis

Por De Vos, Kurt J., Mórotz, Gábor M., Stoica, Radu, Tudor, Elizabeth L., Lau, Kwok-Fai, Ackerley, Steven, Warley, Alice, Shaw, Christopher E., Miller, Christopher C.J.
Publicado em 2012

Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations

Por Godena, Vinay K., Brookes-Hocking, Nicholas, Moller, Annekathrin, Shaw, Gary, Oswald, Matthew, Sancho, Rosa M., Miller, Christopher C. J., Whitworth, Alexander J., De Vos, Kurt J.
Publicado em 2014

ALS/FTD‐associated FUS activates GSK‐3β to disrupt the VAPB–PTPIP51 interaction and ER–mitochondria associations

Por Stoica, Radu, Paillusson, Sébastien, Gomez‐Suaga, Patricia, Mitchell, Jacqueline C, Lau, Dawn HW, Gray, Emma H, Sancho, Rosa M, Vizcay‐Barrena, Gema, De Vos, Kurt J, Shaw, Christopher E, Hanger, Diane P, Noble, Wendy, Miller, Christopher CJ
Publicado no EMBO Rep (2016)

The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy

Por Webster, Christopher P, Smith, Emma F, Bauer, Claudia S, Moller, Annekathrin, Hautbergue, Guillaume M, Ferraiuolo, Laura, Myszczynska, Monika A, Higginbottom, Adrian, Walsh, Matthew J, Whitworth, Alexander J, Kaspar, Brian K, Meyer, Kathrin, Shaw, Pamela J, Grierson, Andrew J, De Vos, Kurt J
Publicado no EMBO J (2016)

C9ORF72 hexanucleotide repeat exerts toxicity in a stable, inducible motor neuronal cell model, which is rescued by partial depletion of Pten

Por Stopford, Matthew J., Higginbottom, Adrian, Hautbergue, Guillaume M., Cooper-Knock, Johnathan, Mulcahy, Padraig J., De Vos, Kurt J., Renton, Alan E., Pliner, Hannah, Calvo, Andrea, Chio, Adriano, Traynor, Bryan J., Azzouz, Mimoun, Heath, Paul R., Kirby, Janine, Shaw, Pamela J.
Publicado no Hum Mol Genet (2017)

ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43

Por Stoica, Radu, De Vos, Kurt J., Paillusson, Sébastien, Mueller, Sarah, Sancho, Rosa M., Lau, Kwok-Fai, Vizcay-Barrena, Gema, Lin, Wen-Lang, Xu, Ya-Fei, Lewis, Jada, Dickson, Dennis W., Petrucelli, Leonard, Mitchell, Jacqueline C., Shaw, Christopher E., Miller, Christopher C. J.
Publicado em 2014

Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content

Por De Vos, Kurt J., Chapman, Anna L., Tennant, Maria E., Manser, Catherine, Tudor, Elizabeth L., Lau, Kwok-Fai, Brownlees, Janet, Ackerley, Steven, Shaw, Pamela J., McLoughlin, Declan M., Shaw, Christopher E., Leigh, P. Nigel, Miller, Christopher C.J., Grierson, Andrew J.
Publicado no Hum Mol Genet (2007)

Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6

Por Vance, Caroline, Rogelj, Boris, Hortobágyi, Tibor, De Vos, Kurt J., Nishimura, Agnes Lumi, Sreedharan, Jemeen, Hu, Xun, Smith, Bradley, Ruddy, Deborah, Wright, Paul, Ganesalingam, Jeban, Williams, Kelly L., Tripathi, Vineeta, Al-Saraj, Safa, Al-Chalabi, Ammar, Leigh, P. Nigel, Blair, Ian P., Nicholson, Garth, de Belleroche, Jackie, Gallo, Jean-Marc, Miller, Christopher C., Shaw, Christopher E.
Publicado no Science (2009)