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Protein Homeostasis in Amyotrophic Lateral Sclerosis: Therapeutic Opportunities?

Protein homeostasis (proteostasis), the correct balance between production and degradation of proteins, is essential for the health and survival of cells. Proteostasis requires an intricate network of protein quality control pathways (the proteostasis network) that work to prevent protein aggregatio...

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Détails bibliographiques
Publié dans:Front Mol Neurosci
Auteurs principaux: Webster, Christopher P., Smith, Emma F., Shaw, Pamela J., De Vos, Kurt J.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411428/
https://ncbi.nlm.nih.gov/pubmed/28512398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00123
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