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Aberrant RNA homeostasis in amyotrophic lateral sclerosis: potential for new therapeutic targets?

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by progressive motor neuron degeneration. The disease pathogenesis is multifaceted in that multiple cellular and molecular pathways have been identified as contributors to the disease progression. Consequently, n...

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Detalhes bibliográficos
Publicado no:Neurodegener Dis Manag
Main Authors: Donnelly, Christopher J, Grima, Jonathan C, Sattler, Rita
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308292/
https://ncbi.nlm.nih.gov/pubmed/25531686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nmt.14.36
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