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Therapeutic Approaches Targeting Protein Aggregation in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a debilitating neurodegenerative disease that targets motor neurons (MNs) in the brain and spinal cord. It leads to gradual loss of motor signals to muscles leading to atrophy and weakness. Most patients do not survive for more than 3–5 years after disease onse...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Malik, Ravinder, Wiedau, Martina
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7296057/
https://ncbi.nlm.nih.gov/pubmed/32581709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.00098
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