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Prion-Like Propagation of Protein Misfolding and Aggregation in Amyotrophic Lateral Sclerosis
The discovery that prion protein can misfold into a pathological conformation that encodes structural information capable of both propagation and inducing severe neuropathology has revolutionized our understanding of neurodegenerative disease. Many neurodegenerative diseases with a protein misfoldin...
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| Udgivet i: | Front Mol Neurosci |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6838634/ https://ncbi.nlm.nih.gov/pubmed/31736708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00262 |
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