Advances in tau-based drug discovery

ανά Noble, Wendy, Pooler, Amy M., Hanger, Diane P.
Έκδοση 2011

A systems approach to personalised nutrition: Report on the Keystone Symposium “Human Nutrition, Environment and Health”

ανά Maher, Michael, Pooler, Amy M., Kaput, James, Kussmann, Martin
Τόπος έκδοσης Appl Transl Genom (2016)

Physiological release of endogenous tau is stimulated by neuronal activity

ανά Pooler, Amy M, Phillips, Emma C, Lau, Dawn H W, Noble, Wendy, Hanger, Diane P
Έκδοση 2013

Propagation of tau pathology in Alzheimer’s disease: identification of novel therapeutic targets

ανά Pooler, Amy M, Polydoro, Manuela, Wegmann, Susanne, Nicholls, Samantha B, Spires-Jones, Tara L, Hyman, Bradley T
Έκδοση 2013

Critical residues involved in tau binding to fyn: implications for tau phosphorylation in Alzheimer’s disease

ανά Lau, Dawn H. W., Hogseth, Marte, Phillips, Emma C., O’Neill, Michael J., Pooler, Amy M., Noble, Wendy, Hanger, Diane P.
Τόπος έκδοσης Acta Neuropathol Commun (2016)

Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons

ανά Rodríguez-Martín, Teresa, Pooler, Amy M., Lau, Dawn H.W., Mórotz, Gábor M., De Vos, Kurt J., Gilley, Jonathan, Coleman, Michael P., Hanger, Diane P.
Τόπος έκδοσης Neurobiol Dis (2016)

Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures

ανά Croft, Cara L, Wade, Matthew A, Kurbatskaya, Ksenia, Mastrandreas, Pavlina, Hughes, Martina M, Phillips, Emma C, Pooler, Amy M, Perkinton, Michael S, Hanger, Diane P, Noble, Wendy
Τόπος έκδοσης Cell Death Dis (2017)

Tau - amyloid interactions in the rTgTauEC model of early Alzheimer’s disease suggest amyloid induced disruption of axonal projections and exacerbated axonal pathology

ανά Pooler, Amy M, Polydoro, Manuela, Wegmann, Susanne K, Pitstick, Rose, Kay, Kevin R, Sanchez, Laura, Carlson, George A, Gomez-Isla, Teresa, Albers, Mark W, Spires-Jones, Tara L, Hyman, Bradley T
Έκδοση 2013

Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer’s disease model

ανά Polydoro, Manuela, Dzhala, Volodymyr I., Pooler, Amy M, Nicholls, Samantha B., McKinney, A. Patrick, Sanchez, Laura, Pitstick, Rose, Carlson, George A., Staley, Kevin J., Spires-Jones, Tara L., Hyman, Bradley T.
Έκδοση 2013

Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer’s disease

ανά Pooler, Amy M, Polydoro, Manuela, Maury, Eduardo A, Nicholls, Samantha B, Reddy, Snigdha M, Wegmann, Susanne, William, Christopher, Saqran, Lubna, Cagsal-Getkin, Ozge, Pitstick, Rose, Beier, David R, Carlson, George A, Spires-Jones, Tara L, Hyman, Bradley T
Τόπος έκδοσης Acta Neuropathol Commun (2015)

Studying synapses in human brain with array tomography and electron microscopy

ανά Kay, Kevin R., Smith, Colin, Wright, Ann K., Serrano-Pozo, Alberto, Pooler, Amy M., Koffie, Robert, Bastin, Mark E., Bak, Thomas H., Abrahams, Sharon, Kopeikina, Katherine J., McGuone, Declan, Frosch, Matthew P., Gillingwater, Thomas H., Hyman, Bradley T., Spires-Jones, Tara L.
Έκδοση 2013

Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity

ανά Wegmann, Susanne, Maury, Eduardo A, Kirk, Molly J, Saqran, Lubna, Roe, Allyson, DeVos, Sarah L, Nicholls, Samantha, Fan, Zhanyun, Takeda, Shuko, Cagsal‐Getkin, Ozge, William, Christopher M, Spires‐Jones, Tara L, Pitstick, Rose, Carlson, George A, Pooler, Amy M, Hyman, Bradley T
Τόπος έκδοσης EMBO J (2015)

Persistent repression of tau in the brain using engineered zinc finger protein transcription factors

ανά Wegmann, Susanne, DeVos, Sarah L., Zeitler, Bryan, Marlen, Kimberly, Bennett, Rachel E., Perez-Rando, Marta, MacKenzie, Danny, Yu, Qi, Commins, Caitlin, Bannon, Riley N., Corjuc, Bianca T., Chase, Alison, Diez, Lisa, Nguyen, Hoang-Oanh B., Hinkley, Sarah, Zhang, Lei, Goodwin, Alicia, Ledeboer, Annemarie, Lam, Stephen, Ankoudinova, Irina, Tran, Hung, Scarlott, Nicholas, Amora, Rainier, Surosky, Richard, Miller, Jeffrey C., Robbins, Ashley B., Rebar, Edward J., Urnov, Fyodor D., Holmes, Michael C., Pooler, Amy M., Riley, Brigit, Zhang, H. Steve, Hyman, Bradley T.
Τόπος έκδοσης Sci Adv (2021)