RML prions act through Mahogunin and Attractin-independent pathways

Por Gunn, Teresa M, Carlson, George A
Publicado em 2013

Neurodegenerative Disease Transmission and Transgenesis in Mice

Por Dugger, Brittany N., Perl, Daniel P., Carlson, George A.
Publicado no Cold Spring Harb Perspect Biol (2017)

Cholesterol transporter ATP-binding cassette A1 (ABCA1) is elevated in prion disease and affects PrP(C) and PrP(Sc) concentrations in cultured cells

Por Kumar, Rajeev, McLain, Denise, Young, Rebecca, Carlson, George A.
Publicado em 2008

Development of a novel cellular model of Alzheimer’s disease utilizing neurosphere cultures derived from B6C3-Tg(APPswe,PSEN1dE9)85Dbo/J embryonic mouse brain

Por Ghate, Pankaj S, Sidhar, Himakshi, Carlson, George A, Giri, Ranjit K
Publicado em 2014

Genotype-Specific Differences between Mouse CNS Stem Cell Lines Expressing Frontotemporal Dementia Mutant or Wild Type Human Tau

Por Orr, Miranda E., Pitstick, Rose, Canine, Brenda, Ashe, Karen H., Carlson, George A.
Publicado em 2012

Tangle-Bearing Neurons Survive Despite Disruption of Membrane Integrity in a Mouse Model of Tauopathy

Por de Calignon, Alix, Spires-Jones, Tara L., Pitstick, Rose, Carlson, George A., Hyman, Bradley T.
Publicado em 2009

Improvement of ENU Mutagenesis Efficiency Using Serial Injection and Mismatch Repair Deficiency Mice

Por Gallego-Llamas, Jabier, Timms, Andrew E., Pitstick, Rose, Peters, Janet, Carlson, George A., Beier, David R.
Publicado no PLoS One (2016)

Prion infection of mouse neurospheres

Por Giri, Ranjit K., Young, Rebecca, Pitstick, Rose, DeArmond, Stephen J., Prusiner, Stanley B., Carlson, George A.
Publicado em 2006

Inhibition of Sirtuin 2 with Sulfobenzoic Acid Derivative AK1 is Non-Toxic and Potentially Neuroprotective in a Mouse Model of Frontotemporal Dementia

Por Spires-Jones, Tara L., Fox, Leora M., Rozkalne, Anete, Pitstick, Rose, Carlson, George A., Kazantsev, Aleksey G.
Publicado em 2012

Knockout of the prion protein (PrP)-like Sprn gene does not produce embryonic lethality in combination with PrP(C)-deficiency

Por Daude, Nathalie, Wohlgemuth, Serene, Brown, Rebecca, Pitstick, Rose, Gapeshina, Hristina, Yang, Jing, Carlson, George A., Westaway, David
Publicado em 2012

Methylene blue does not reverse existing neurofibrillary tangle pathology in the rTg4510 mouse model of tauopathy

Por Spires-Jones, Tara L, Friedman, Taylor, Pitstick, Rose, Polydoro, Manuela, Roe, Allyson, Carlson, George A, Hyman, Bradley T
Publicado em 2014

Region-specific Dissociation of Neuronal Loss and Neurofibrillary Pathology in a Mouse Model of Tauopathy

Por Spires, Tara L., Orne, Jennifer D., SantaCruz, Karen, Pitstick, Rose, Carlson, George A., Ashe, Karen H., Hyman, Bradley T.
Publicado em 2006

Caspase activation precedes and leads to tangles

Por de Calignon, Alix, Fox, Leora M., Pitstick, Rose, Carlson, George A., Bacskai, Brian J., Spires-Jones, Tara L., Hyman, Bradley T.
Publicado em 2010

Soluble Tau Species, Not Neurofibrillary Aggregates, Disrupt Neural System Integration in a Tau Transgenic Model

Por Fox, Leora M., William, Christopher M., Adamowicz, David H., Pitstick, Rose, Carlson, George A, Spires-Jones, Tara L, Hyman, Bradley T.
Publicado em 2011

Aβ1–40-related reduction in functional hyperemia in mouse neocortex during somatosensory activation

Por Niwa, Kiyoshi, Younkin, Linda, Ebeling, Christine, Turner, Sherry K., Westaway, David, Younkin, Steven, Ashe, Karen Hsiao, Carlson, George A., Iadecola, Costantino
Publicado em 2000

Synaptic alterations in the rTg4510 mouse model of tauopathy

Por Kopeikina, Katherine J, Polydoro, Manuela, Tai, Hwan-Ching, Yaeger, Erich, Carlson, George A, Pitstick, Rose, Hyman, Bradley T, Spires-Jones, Tara L
Publicado em 2013

Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice

Por Johnson, Noah R., Condello, Carlo, Guan, Shenheng, Oehler, Abby, Becker, Julia, Gavidia, Marta, Carlson, George A., Giles, Kurt, Prusiner, Stanley B.
Publicado no Proc Natl Acad Sci U S A (2017)

The Effect of HIV Protease Inhibitors on Amyloid-β Peptide Degradation and Synthesis in Human Cells and Alzheimer’s Disease Animal Model

Por Lan, Xiqian, Kiyota, Tomomi, Hanamsagar, Richa, Huang, Yunlong, Andrews, Scott, Peng, Hui, Zheng, Jialin C., Swindells, Susan, Carlson, George A., Ikezu, Tsuneya
Publicado em 2011

Levels of the Mahogunin Ring Finger 1 E3 Ubiquitin Ligase Do Not Influence Prion Disease

Por Silvius, Derek, Pitstick, Rose, Ahn, Misol, Meishery, Delisha, Oehler, Abby, Barsh, Gregory S., DeArmond, Stephen J., Carlson, George A., Gunn, Teresa M.
Publicado em 2013

Tau Causes Synapse Loss without Disrupting Calcium Homeostasis in the rTg4510 Model of Tauopathy

Por Kopeikina, Katherine J., Wegmann, Susanne, Pitstick, Rose, Carlson, George A., Bacskai, Brian J., Betensky, Rebecca A., Hyman, Bradley T., Spires-Jones, Tara L.
Publicado em 2013