Knockout of the prion protein (PrP)-like Sprn gene does not produce embryonic lethality in combination with PrP(C)-deficiency

The Sprn gene encodes Shadoo (Sho), a glycoprotein with biochemical properties similar to the unstructured region of cellular prion protein (PrP(C)). Sho has been considered a candidate for the hypothetical π protein that supplies a PrP(C)-like function to maintain the viability of Prnp(0/0) mice la...

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Bibliografski detalji
Glavni autori: Daude, Nathalie, Wohlgemuth, Serene, Brown, Rebecca, Pitstick, Rose, Gapeshina, Hristina, Yang, Jing, Carlson, George A., Westaway, David
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384183/
https://ncbi.nlm.nih.gov/pubmed/22619325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202130109
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