Synaptic alterations in the rTg4510 mouse model of tauopathy

Synapse loss, rather than the hallmark amyloid-β (Aβ) plaques or tau filled neurofibrillary tangles (NFT), is considered the most predictive pathological feature associated with cognitive status in the Alzheimer disease (AD) brain. The role of Aβ in synapse loss is well established, but despite data...

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Hauptverfasser: Kopeikina, Katherine J, Polydoro, Manuela, Tai, Hwan-Ching, Yaeger, Erich, Carlson, George A, Pitstick, Rose, Hyman, Bradley T, Spires-Jones, Tara L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725804/
https://ncbi.nlm.nih.gov/pubmed/23047530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.23234
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