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Synaptic alterations in the rTg4510 mouse model of tauopathy
Synapse loss, rather than the hallmark amyloid-β (Aβ) plaques or tau filled neurofibrillary tangles (NFT), is considered the most predictive pathological feature associated with cognitive status in the Alzheimer disease (AD) brain. The role of Aβ in synapse loss is well established, but despite data...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3725804/ https://ncbi.nlm.nih.gov/pubmed/23047530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.23234 |
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