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Synaptic alterations in the rTg4510 mouse model of tauopathy

Synapse loss, rather than the hallmark amyloid-β (Aβ) plaques or tau filled neurofibrillary tangles (NFT), is considered the most predictive pathological feature associated with cognitive status in the Alzheimer disease (AD) brain. The role of Aβ in synapse loss is well established, but despite data...

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書誌詳細
主要な著者: Kopeikina, Katherine J, Polydoro, Manuela, Tai, Hwan-Ching, Yaeger, Erich, Carlson, George A, Pitstick, Rose, Hyman, Bradley T, Spires-Jones, Tara L
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725804/
https://ncbi.nlm.nih.gov/pubmed/23047530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.23234
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