Synaptic alterations in the rTg4510 mouse model of tauopathy

Synapse loss, rather than the hallmark amyloid-β (Aβ) plaques or tau filled neurofibrillary tangles (NFT), is considered the most predictive pathological feature associated with cognitive status in the Alzheimer disease (AD) brain. The role of Aβ in synapse loss is well established, but despite data...

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Hlavní autoři: Kopeikina, Katherine J, Polydoro, Manuela, Tai, Hwan-Ching, Yaeger, Erich, Carlson, George A, Pitstick, Rose, Hyman, Bradley T, Spires-Jones, Tara L
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725804/
https://ncbi.nlm.nih.gov/pubmed/23047530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.23234
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