Tracking progressive pathological and functional decline in the rTg4510 mouse model of tauopathy

BACKGROUND: The choice and appropriate use of animal models in drug discovery for Alzheimer’s disease (AD) is pivotal to successful clinical translation of novel therapeutics, yet true alignment of research is challenging. Current models do not fully recapitulate the human disease, and even exhibit...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Blackmore, Thomas, Meftah, Soraya, Murray, Tracey Karen, Craig, Peter James, Blockeel, Anthony, Phillips, Keith, Eastwood, Brian, O’Neill, Michael J., Marston, Hugh, Ahmed, Zeshan, Gilmour, Gary, Gastambide, Francois
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607580/
https://ncbi.nlm.nih.gov/pubmed/28931441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-017-0306-2
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