Age-Dependent Impairment of Cognitive and Synaptic Function in the htau Mouse Model of Tau Pathology

Por Polydoro, Manuela, Acker, Christopher M., Duff, Karen, Castillo, Pablo E., Davies, Peter
Publicado em 2009

The intersection of amyloid beta and tau in glutamatergic synaptic dysfunction and collapse in Alzheimer’s disease

Por Crimins, Johanna L., Pooler, Amy, Polydoro, Manuela, Luebke, Jennifer I., Spires-Jones, Tara L.
Publicado em 2013

Propagation of tau pathology in Alzheimer’s disease: identification of novel therapeutic targets

Por Pooler, Amy M, Polydoro, Manuela, Wegmann, Susanne, Nicholls, Samantha B, Spires-Jones, Tara L, Hyman, Bradley T
Publicado em 2013

Methylene blue does not reverse existing neurofibrillary tangle pathology in the rTg4510 mouse model of tauopathy

Por Spires-Jones, Tara L, Friedman, Taylor, Pitstick, Rose, Polydoro, Manuela, Roe, Allyson, Carlson, George A, Hyman, Bradley T
Publicado em 2014

Synaptic alterations in the rTg4510 mouse model of tauopathy

Por Kopeikina, Katherine J, Polydoro, Manuela, Tai, Hwan-Ching, Yaeger, Erich, Carlson, George A, Pitstick, Rose, Hyman, Bradley T, Spires-Jones, Tara L
Publicado em 2013

Identification of Small Molecule Inhibitors of Neurite Loss Induced by Aβ peptide using High Content Screening

Por Ofengeim, Dimitry, Shi, Peng, Miao, Benchun, Fan, Jing, Xia, Xiaofeng, Fan, Yubo, Lipinski, Marta M., Hashimoto, Tadafumi, Polydoro, Manuela, Yuan, Junying, Wong, Stephen T. C., Degterev, Alexei
Publicado em 2012

αβγ-Synuclein triple knockout mice reveal age-dependent neuronal dysfunction

Por Greten-Harrison, Becket, Polydoro, Manuela, Morimoto-Tomita, Megumi, Diao, Ling, Williams, Andrew M., Nie, Esther H., Makani, Sachin, Tian, Ning, Castillo, Pablo E., Buchman, Vladimir L., Chandra, Sreeganga S.
Publicado em 2010

Tau - amyloid interactions in the rTgTauEC model of early Alzheimer’s disease suggest amyloid induced disruption of axonal projections and exacerbated axonal pathology

Por Pooler, Amy M, Polydoro, Manuela, Wegmann, Susanne K, Pitstick, Rose, Kay, Kevin R, Sanchez, Laura, Carlson, George A, Gomez-Isla, Teresa, Albers, Mark W, Spires-Jones, Tara L, Hyman, Bradley T
Publicado em 2013

Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer’s disease model

Por Polydoro, Manuela, Dzhala, Volodymyr I., Pooler, Amy M, Nicholls, Samantha B., McKinney, A. Patrick, Sanchez, Laura, Pitstick, Rose, Carlson, George A., Staley, Kevin J., Spires-Jones, Tara L., Hyman, Bradley T.
Publicado em 2013

Propagation of tau pathology in a model of early Alzheimer’s disease

Por de Calignon, Alix, Polydoro, Manuela, Suárez-Calvet, Marc, William, Christopher, Adamowicz, David H., Kopeikina, Kathy J., Pitstick, Rose, Sahara, Naruhiko, Ashe, Karen H., Carlson, George A., Spires-Jones, Tara L., Hyman, Bradley T.
Publicado em 2012

Reversal of Neurofibrillary Tangles and Tau-Associated Phenotype in the rTgTauEC Model of Early Alzheimer's Disease

Por Polydoro, Manuela, de Calignon, Alix, Suárez-Calvet, Marc, Sanchez, Laura, Kay, Kevin R., Nicholls, Samantha B., Roe, Allyson D., Pitstick, Rose, Carlson, George A., Gómez-Isla, Teresa, Spires-Jones, Tara L., Hyman, Bradley T.
Publicado em 2013

Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer’s disease

Por Pooler, Amy M, Polydoro, Manuela, Maury, Eduardo A, Nicholls, Samantha B, Reddy, Snigdha M, Wegmann, Susanne, William, Christopher, Saqran, Lubna, Cagsal-Getkin, Ozge, Pitstick, Rose, Beier, David R, Carlson, George A, Spires-Jones, Tara L, Hyman, Bradley T
Publicado no Acta Neuropathol Commun (2015)