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Identification of Small Molecule Inhibitors of Neurite Loss Induced by Aβ peptide using High Content Screening

Multiple lines of evidence indicate a strong relationship between Αβ peptide-induced neurite degeneration and the progressive loss of cognitive functions in Alzheimer disease (AD) patients and in AD animal models. This prompted us to develop a high content screening assay (HCS) and Neurite Image Qua...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ofengeim, Dimitry, Shi, Peng, Miao, Benchun, Fan, Jing, Xia, Xiaofeng, Fan, Yubo, Lipinski, Marta M., Hashimoto, Tadafumi, Polydoro, Manuela, Yuan, Junying, Wong, Stephen T. C., Degterev, Alexei
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308767/
https://ncbi.nlm.nih.gov/pubmed/22277654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.290957
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