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Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases

Apoptosis is crucial for the normal development of the nervous system, whereas neurons in the adult CNS are relatively resistant to this form of cell death. However, under pathological conditions, upregulation of death receptor family ligands, such as tumour necrosis factor (TNF), can sensitize cell...

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Detalhes bibliográficos
Publicado no:Nat Rev Neurosci
Main Authors: Yuan, Junying, Amin, Palak, Ofengeim, Dimitry
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342007/
https://ncbi.nlm.nih.gov/pubmed/30467385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41583-018-0093-1
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