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Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases

Apoptosis is crucial for the normal development of the nervous system, whereas neurons in the adult CNS are relatively resistant to this form of cell death. However, under pathological conditions, upregulation of death receptor family ligands, such as tumour necrosis factor (TNF), can sensitize cell...

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Bibliografische gegevens
Gepubliceerd in:Nat Rev Neurosci
Hoofdauteurs: Yuan, Junying, Amin, Palak, Ofengeim, Dimitry
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342007/
https://ncbi.nlm.nih.gov/pubmed/30467385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41583-018-0093-1
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