Tau - amyloid interactions in the rTgTauEC model of early Alzheimer’s disease suggest amyloid induced disruption of axonal projections and exacerbated axonal pathology

Early observations of the patterns of neurofibrillary tangles and amyloid plaques in Alzheimer’s disease suggested a hierarchical vulnerability of neurons for tangles, and a widespread nonspecific pattern of plaques that nonetheless seemed to correlate with the terminal zone of tangle bearing neuron...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Pooler, Amy M, Polydoro, Manuela, Wegmann, Susanne K, Pitstick, Rose, Kay, Kevin R, Sanchez, Laura, Carlson, George A, Gomez-Isla, Teresa, Albers, Mark W, Spires-Jones, Tara L, Hyman, Bradley T
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797265/
https://ncbi.nlm.nih.gov/pubmed/23839581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.23411
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge