Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer’s disease

INTRODUCTION: In early stages of Alzheimer’s disease (AD), neurofibrillary tangles (NFT) are largely restricted to the entorhinal cortex and medial temporal lobe. At later stages, when clinical symptoms generally occur, NFT involve widespread limbic and association cortices. At this point in the dis...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Acta Neuropathol Commun
Hlavní autoři: Pooler, Amy M, Polydoro, Manuela, Maury, Eduardo A, Nicholls, Samantha B, Reddy, Snigdha M, Wegmann, Susanne, William, Christopher, Saqran, Lubna, Cagsal-Getkin, Ozge, Pitstick, Rose, Beier, David R, Carlson, George A, Spires-Jones, Tara L, Hyman, Bradley T
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371800/
https://ncbi.nlm.nih.gov/pubmed/25853174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0199-x
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky