Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer’s disease

INTRODUCTION: In early stages of Alzheimer’s disease (AD), neurofibrillary tangles (NFT) are largely restricted to the entorhinal cortex and medial temporal lobe. At later stages, when clinical symptoms generally occur, NFT involve widespread limbic and association cortices. At this point in the dis...

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Detaylı Bibliyografya
Yayımlandı:Acta Neuropathol Commun
Asıl Yazarlar: Pooler, Amy M, Polydoro, Manuela, Maury, Eduardo A, Nicholls, Samantha B, Reddy, Snigdha M, Wegmann, Susanne, William, Christopher, Saqran, Lubna, Cagsal-Getkin, Ozge, Pitstick, Rose, Beier, David R, Carlson, George A, Spires-Jones, Tara L, Hyman, Bradley T
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2015
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371800/
https://ncbi.nlm.nih.gov/pubmed/25853174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0199-x
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